Synergistic antitumor effects of combined deguelin and cisplatin treatment in gastric cancer cells

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Synergistic antitumor effects of combined deguelin and cisplatin treatment in gastric cancer cells

Deguelin is a naturally occurring rotenoid with marked chemopreventive and antitumor activity. Cisplatin, characterized by damaging DNA, is widely used in the chemotherapy of malignancies, including gastric cancer. The present study investigated whether synergistic effects exist between the combination of deguelin and cisplatin, and the possible mechanism in vitro. The interactive effects of de...

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ژورنال

عنوان ژورنال: Oncology Letters

سال: 2014

ISSN: 1792-1074,1792-1082

DOI: 10.3892/ol.2014.2368